Papers published in the first 50 years since its establishment (1971- 2020)

[1] Research conducted primarily by our department

Top 10 Most-Cited Papers (Scopus, September 2025)

On the Cover (Acute phosphate nephropathy).
Mizuno S, Kounoue N, Sanada S, Sato T. Clin J Am Soc Nephrol. 2020 Dec;15(12).

Successful management of hemodialysis-dependent refractory myeloma with modified daratumumab, bortezomib and dexamethasone regimen.
Mizuno S, Kitayama C, Yamaguchi K, Sanada S, Sato T. Int J Hematol. 2020 Dec;112(6):860-863.

Light chain deposition disease without proteinuria.
Mizuno S, Kitayama C. EJHaem. 2020 Sep 16;1(2):409-410.

Pathological value of lysozyme staining for renal sarcoidosis.
Sanada S, Yoda S, Sato T. Nephrol Dial Transplant. 2020 Sep 1;35(9):1638-1641.

Chemokine Receptor 8 Can Distinguish Antineutrophil Cytoplasmic Antibody-Associated Vasculitis From Infectious Complications.
Sanada S, Akiyama Y, Sato M, Sato T, Taguma Y. Kidney Int Rep. 2018 Nov 10;4(3):447-454.

Suboptimal initiation predicts short-term prognosis and vulnerability among very elderly patients who start haemodialysis.
Kanno A, Nakayama M, Sanada S, Sato M, Sato T, Taguma Y.
Nephrology (Carlton). 2019 Jan;24(1):94-101.

Efficacy of statin on vascular access patency in diabetic hemodialysis patients.
Sanada S, Miyasaka Y, Kanno A, Sato K, Sato M, Sugai H, Kitamura H, Sato T, Taguma Y. J Vasc Access. 2017 Jul 14;18(4):295-300.

The size of palatine tonsils cannot be used to decide the indication of tonsillectomy for IgA nephropathy.
Sato M, Adachi M, Kosukegawa H, Nomura Y, Watanabe K, Sato T, Taguma Y.
Clin Kidney J. 2017 Apr;10(2):221-228.

Efficacy of low-density lipoprotein apheresis combined with corticosteroids for cholesterol crystal embolism.
Ishiyama K, Sato T, Yamaguchi T, Taguma Y.
Clin Exp Nephrol. 2017 Apr;21(2):228-235.

Renal Improvement With Molecular-Selective Plasma Exchange in a Patient With Bence-Jones Type Multiple Myeloma.
Kanda M, Sanada S, Kowata H, Mizuno S, Yamakage S, Sato M, Sato T, Taguma Y.
Ther Apher Dial. 2016 Aug;20(4):420-2.

Low-Density Lipoprotein Apheresis Ameliorates Renal Prognosis of Cholesterol Crystal Embolism.
Ishiyama K, Sato T, Taguma Y.
Ther Apher Dial. 2015 Aug;19(4):355-60.

Proliferative glomerulonephritis with monoclonal IgM-κ deposits in chronic lymphocytic leukemia/small lymphocytic leukemia: case report and review of the literature.
Oe Y, Joh K, Sato M, Taguma Y, Onishi Y, Nakayama K, Sato T.
CEN Case Rep. 2013 Nov;2(2):222-227.

Significance of the duration of nephropathy for achieving clinical remission in patients with IgA nephropathy treated by tonsillectomy and steroid pulse therapy.
Ieiri N, Hotta O, Sato T, Taguma Y.
Clin Exp Nephrol. 2012 Feb;16(1):122-9.

Clinical effectiveness of steroid pulse therapy combined with tonsillectomy in patients with immunoglobulin A nephropathy presenting glomerular haematuria and minimal proteinuria.
Kawaguchi T, Ieiri N, Yamazaki S, Hayashino Y, Gillespie B, Miyazaki M, Taguma Y, Fukuhara S, Hotta O.
Nephrology (Carlton). 2010 Feb;15(1):116-23.

High prevalence of Chlamydophila pneumoniae infection in patients with myeloperoxidase antineutrophil cytoplasmic autoantibody (MPO-ANCA)-associated glomerulonephritis.
Kawaguchi T, Yusa N, Taguma Y, Hotta O.
NDT Plus. 2008 Dec;1(6):468.

Impact of annual urine health check-up system to obtain clinical remission in patients with IgA nephropathy.
Ieiri N, Hotta O, Taguma Y.
Contrib Nephrol. 2007;157:104-8.

A multicenter prospective cohort study of tonsillectomy and steroid therapy in Japanese patients with IgA nephropathy: a 5-year report.
Miyazaki M, Hotta O, Komatsuda A, Nakai S, Shoji T, Yasunaga C, Taguma Y; Japanese Multicenter Study Group on Treatment of IgA Nephropathy (JST-IgAN).
Contrib Nephrol. 2007;157:94-8.

Predictive factors of clinical outcome in patients with diffuse proliferative lupus nephritis treated early by intravenous methylprednisolone pulse therapy.
Kanno A, Hotta O, Yusa N, Taguma Y.
Ren Fail. 2007;29(1):41-7.

Improvements in treatment strategies for patients with antineutrophil cytoplasmic antibody-associated rapidly progressive glomerulonephritis.
Hotta O, Ishida A, Kimura T, Taguma Y.
Ther Apher Dial. 2006 Oct;10(5):390-5.

Characteristics of acute glomerulonephritis associated with human parvovirus B19 infection.
Ieiri N, Hotta O, Taguma Y.
Clin Nephrol. 2005 Oct;64(4):249-57.

Can minimal change nephrotic syndrome superimposed on diabetic nephropathy be diagnosed?
Sanada S, Hotta O, Sato M, Taguma Y.
Clin Nephrol. 2005 Jul;64(1):81-2.

Predictive value of urinary micro-cholesterol (mCHO) levels in patients with progressive glomerular disease.
Hotta O, Sugai H, Kitamura H, Yusa N, Taguma Y.
Kidney Int. 2004 Dec;66(6):2374-81.

Cohort study of advanced IgA nephropathy: efficacy and limitations of corticosteroids with tonsillectomy.
Sato M, Hotta O, Tomioka S, Horigome I, Chiba S, Miyazaki M, Noshiro H, Taguma Y.
Nephron Clin Pract. 2003;93(4):c137-45.

Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy.
Ieiri N, Hotta O, Taguma Y.
Am J Kidney Dis. 2003 Jan;41(1):244-9.

Decreased CD4 lymphocyte count as a marker predicting high mortality rate in managing ANCA related rapidly progressive glomerulonephritis.
Furuta T, Hotta O, Horigome I, Chiba S, Noshiro H, Miyazaki M, Satoh M, Honda S, Taguma Y.
Nephron. 2002 Aug;91(4):601-5.

Resolution of nodular glomerular lesions in a patient with light-chain nephropathy.
Hotta O, Taguma Y.
Nephron. 2002 Jul;91(3):504-5.

Glomerulo-tubular junction stenosis as a factor contributing to glomerular obsolescence in IgA nephropathy.
Sato M, Hotta O, Taguma Y.
J Pathol. 2002 May;197(1):14-9.

Regression of IgA nephropathy: a repeat biopsy study.
Hotta O, Furuta T, Chiba S, Tomioka S, Taguma Y.
Am J Kidney Dis. 2002 Mar;39(3):493-502.

Evaluation of coagulation and fibrinolysis in haemodialysis patients at different haematocrit levels: Comparison between patients with and without diabetes.
Sato M, Ohgiya H, Taguma Y.
Nephrology. 2002 Feb;7(1):37-42.

Steroid pulse therapy combined with tonsillectomy in IgA nephropathy associated with diabetes mellitus.
Furuta T, Hotta O, Horigome I, Chiba S, Noshiro H, Miyazaki M, Satoh M, Honda S, Taguma Y.
Nephron. 2001 Dec;89(4):398-401.

Tonsillectomy and steroid pulse therapy significantly impact on clinical remission in patients with IgA nephropathy.
Hotta O, Miyazaki M, Furuta T, Tomioka S, Chiba S, Horigome I, Abe K, Taguma Y.
Am J Kidney Dis. 2001 Oct;38(4):736-43.

Autonomic insufficiency as a factor contributing to dialysis-induced hypotension.
Sato M, Horigome I, Chiba S, Furuta T, Miyazaki M, Hotta O, Suzuki K, Noshiro H, Taguma Y.
Nephrol Dial Transplant. 2001 Aug;16(8):1657-62.

Clinical and pathologic features of focal segmental glomerulosclerosis with mitochondrial tRNALeu(UUR) gene mutation.
Hotta O, Inoue CN, Miyabayashi S, Furuta T, Takeuchi A, Taguma Y.
Kidney Int. 2001 Apr;59(4):1236-43.

Urinary macrophages as activity markers of renal injury.
Hotta O, Yusa N, Kitamura H, Taguma Y.
Clin Chim Acta. 2000 Jul;297(1-2):123-33.

Usefulness of serum cystatin-C as a marker of the renal function: a comparative evaluation with beta 2-microglobulin, alpha 1-microglobulin and creatinine.
Hotta O, Yusa N, Mukaiyama I, Taguma Y.
Nihon Jinzo Gakkai Shi. 1999 Dec;41(8):797-803.

Immunosuppressive effect of deoxyspergualin in proliferative glomerulonephritis.
Hotta O, Furuta T, Chiba S, Yusa N, Taguma Y.
Am J Kidney Dis. 1999 Nov;34(5):894-901.

Detection of urinary macrophages expressing the CD16 (Fc gamma RIII) molecule: a novel marker of acute inflammatory glomerular injury.
Hotta O, Yusa N, Ooyama M, Unno K, Furuta T, Taguma Y.
Kidney Int. 1999 May;55(5):1927-34.

Pathogenic role of glomerulo-tubular junction stenosis in glomerulocystic disease.
Hotta O, Sato M, Furuta T, Taguma Y.
Clin Nephrol. 1999 Mar;51(3):177-80.

Effects of deoxyspergualin on proliferative glomerulonephritis.
Hotta O, Ito K, Furuta T, Chiba S, Taguma Y.
Nihon Jinzo Gakkai Shi. 1999 Jan;41(1):21-8.

Lymphocytapheresis to treat rapidly progressive glomerulonephritis: a randomised comparison with steroid-pulse treatment.
Furuta T, Hotta O, Yusa N, Horigome I, Chiba S, Taguma Y.
Lancet. 1998 Jul 18;352(9123):203-4.

Detection of mature macrophages in urinary sediments: clinical significance in predicting progressive renal disease.
Hotta O, Kitamura H, Taguma Y.
Ren Fail. 1998 Mar;20(2):413-8.

Membranoproliferative glomerulonephritis in the aged and its possible causal relationship with CD8+CD57+ lymphocytes.
Hotta O, Yusa N, Furuta T, Onodera S, Kitamura H, Taguma Y.
Clin Nephrol. 1998 Mar;49(3):138-44.
Clinicopathological significance of intratubular giant macrophages in progressive glomerulonephritis.
Oda T, Hotta O, Taguma Y, Kitamura H, Sugai H, Onodera S, Horigome I, Suzuki K, Shouji Y, Furuta T, Chiba S, Yoshizawa N, Nagura H.
Kidney Int. 1998 May;53(5):1190-200.

Glomerular proliferating cell kinetics in acute post-streptococcal glomerulonephritis (APSGN).
Oda T, Yoshizawa N, Takeuchi A, Nakabayashi I, Nishiyama J, Ishida A, Tazawa K, Murayama M, Hotta O, Taguma Y.
J Pathol. 1997 Nov;183(3):359-68.

Involvement of neutrophil elastase in crescentic glomerulonephritis.
Oda T, Hotta O, Taguma Y, Kitamura H, Sudo K, Horigome I, Chiba S, Yoshizawa N, Nagura H.
Hum Pathol. 1997 Jun;28(6):720-8.

Reduced reticulization of palatine tonsils with IgA nephropathy.
Sato Y, Hotta O, Taguma Y, Takasaka T, Nose M.
Acta Otolaryngol Suppl. 1996;523:189-92.

Clinical study of chronic tonsillitis with IgA nephropathy treated by tonsillectomy.
Tomioka S, Miyoshi K, Tabata K, Hotta O, Taguma Y.
Acta Otolaryngol Suppl. 1996;523:175-7.

IgA nephropathy with poorly developed lymphoepithelial symbiosis of the palatine tonsils.
Sato Y, Hotta O, Taguma Y, Takasaka T, Nose M.
Nephron. 1996;74(2):301-8.

Role of neutrophil elastase in the development of renal necrotizing vasculitis.
Hotta O, Oda T, Taguma Y, Kitamura H, Chiba S, Miyazawa S, Nagura H.
Clin Nephrol. 1996 Apr;45(4):211-6.

Possible relationship between hyperinsulinemia and glomerular hypertrophy in nephrosclerosis.
Hotta O, Taguma Y, Chiba S, Sudou K, Horigome I, Yusa N, Furuta T.
Ren Fail. 1996 Mar;18(2):271-8.

Long-term effects of intensive therapy combined with tonsillectomy in patients with IgA nephropathy.
Hotta O, Taguma Y, Yoshizawa N, Oda T, Nishiyama J, Yusa N, Chiba S, Horigome I, Sudo K, Tomioka S.
Acta Otolaryngol Suppl. 1996;523:165-8.

Successful treatment of interstitial pneumonitis with cyclosporin A in a patient with rheumatoid arthritis accompanied by acute interstitial nephritis.
Miyazawa S, Hotta O, Kitamura H, Sudou K, Horigome I, Chiba S, Tokoi T, Taguma Y.
Nihon Jinzo Gakkai Shi. 1996 Jan;38(1):33-9.

Urinary macrophage counts and ratio to T lymphocytes: possible use in differential diagnosis and management of glomerular disease.
Hotta O, Yusa N, Ooyama M, Taguma Y.
J Clin Lab Anal. 1996;10(4):205-8.

Soluble ELAM-1 is elevated with the progression of IgA nephropathy but not with that of polycystic kidney disease.
Hotta O, Taguma Y, Yusa N, Kitamura H, Sudo K, Horigome I.
Nephron. 1996;72(4):736-8.

Clinicopathological study of IgA nephropathy in patients with congenitally reduced nephron mass.
Hotta O, Chiba S, Furuta T, Sudou K, Horigome I, Taguma Y.
Clin Nephrol. 1995 Dec;44(6):362-6.

Mesangiolysis associated with severe glomerular endocapillary proliferation of CD57 large granular lymphocytes.
Hotta O, Miyazawa S, Taguma Y, Onodera S, Kitamura H, Yusa N, Nakamura K.
Clin Nephrol. 1995 May;43(5):297-302.
Analysis of mononuclear cells in urine using flow cytometry in glomerular diseases.
Hotta O, Taguma Y, Yusa N, Ooyama M.
Kidney Int Suppl. 1994 Nov;47:S117-21.

A case of IgA nephropathy with numerous interstitial foam cells--analysis of infiltrating mononuclear leucocytes in renal tissue.
Kurihara I, Hotta O, Taguma Y, Kurosawa K, Sudo K, Horigome I, Munakata T, Hirai M, Soma J, Sato H, et al.
Nihon Jinzo Gakkai Shi. 1994 Jun;36(6):774-8.

Usefulness of dialysate fibrin degradation products and lactic dehydrogenase isoenzyme patterns in assessing the clinical course of peritonitis.
Suzuki K, Ishizaki M, Hotta O, Horigome I, Sudo K, Kurosawa K, Taguma Y.
Perit Dial Int. 1994;14(3):231-5.

Predictive value of small crescents in IgA nephropathy: analysis of four patients showing a deteriorated renal function during a long follow-up period.
Hotta O, Taguma Y, Kurosawa K, Sudo K, Suzuki K, Horigome I.
Clin Nephrol. 1993 Sep;40(3):125-30.

Early intensive therapy for clinical remission of active IgA nephropathy: a three-year follow-up study.
Hotta O, Taguma Y, Kurosawa K, Sudo K, Suzuki K, Horigome I.
Nihon Jinzo Gakkai Shi. 1993 Aug;35(8):967-73.

Analysis of CD14+ cells and CD56+ cells in urine using flow cytometry: a useful tool for monitoring disease activity of IgA nephropathy.
Hotta O, Taguma Y, Ooyama M, Yusa N, Nagura H.
Clin Nephrol. 1993 Jun;39(6):289-94.

Membranous nephropathy associated with nodular sclerosing Hodgkin's disease.
Hotta O, Taguma Y, Kurosawa K, Sudo K, Takahashi H.
Nephron. 1993;63(3):347-50.

Limitation of kidney biopsy in detecting crescentic lesions in IgA nephropathy.
Hotta O, Taguma Y, Sudo K, Kurosawa K.
Nephron. 1993;65(3):472-3.

Liposarcoma of the renal capsule.
Sasagawa I, Suzuki K, Ishizaki M, Takahashi H, Taguma Y, Nakamura K, Suzuki K.
Urol Int. 1992;48(2):223-5.

Analysis of mononuclear cells in urine using flow cytometry: a useful tool for monitoring disease activity of proliferative glomerulonephritis.
Hotta O, Taguma Y, Yusa N, Sudo K, Kurosawa K, Suzuki K, Takahashi H.
Nihon Jinzo Gakkai Shi. 1992 Jul;34(7):753-9.

Successful treatment with steroid pulse therapy in a case of dilated cardiomyopathy associated with mesangial proliferative glomerulonephritis.
Furuta T, Taguma Y, Hotta O, Kurosawa K, Sudo K, Suzuki K, Meguro Y, Takahashi H.
Nihon Jinzo Gakkai Shi. 1992 Jun;34(6):725-9.

Anti-proteinuric and anti-coagulatory effects of camostat mesilate in azotemic diabetics.
Matsubara M, Taguma Y, Saito T, Yoshinaga K.
Nihon Jinzo Gakkai Shi. 1992 Apr;34(4):411-6.

Effect of camostat mesilate on persistent proteinuria of IgA nephropathy.
Matsubara M, Taguma Y, Saito T, Yoshinaga K.
Nephron. 1992;60(2):244-5.

A case of renal failure due to primary cholesterol atheroembolism.
Matsubara M, Taguma Y, Hotta O, Kurosawa K, Nakamura K, Matsui K.
Nihon Jinzo Gakkai Shi. 1991 Apr;33(4):417-21.
Oral high dose 1,25(OH)2D3 pulse therapy.
Matsubara M, Sugai H, Taguma Y, Suzuki K, Ishizaki M, Takahashi H.
Nihon Jinzo Gakkai Shi. 1991 Feb;33(2):119-23.

Urinary albumin excretion in patients with non-insulin-dependent diabetes mellitus in an early microalbuminuric stage.
Hotta O, Taguma Y, Mitsuoka M, Takeshita K, Takahashi H.
Nephron. 1991;58(1):23-6.

Mode of progression of secondary hyperparathyroidism in patients with chronic renal failure.
Matsubara M, Sugai H, Taguma Y, Ishizaki M, Suzuki K, Takahashi H, Saito T, Yoshinaga K.
Nephron. 1991;58(1):122-3.

CD16+ and CD56+ cells as markers of necrotizing and crescentic glomerulonephritis and active IgA glomerulonephropathy.
Hotta O, Seki S, Taguma Y, Shimoda A, Abo T, Takahashi H.
Nephron. 1991;57(2):239-40.

Effect of camostat mesilate for the treatment of advanced diabetic nephropathy.
Matsubara M, Taguma Y, Kurosawa K, Hotta O, Suzuki K, Ishizaki M.
J Lab Clin Med. 1990 Aug;116(2):206-10.

Clinico-pathological features in four patients with Fabry's disease. The possible role of degenerative lesions in the interstitial vessels in renal dysfunction.
Matsubara M, Taguma Y, Saito T, Yoshinaga K, Furuyama T, Sakaguchi H.
Nihon Jinzo Gakkai Shi. 1990 Feb;32(2):237-43.

Effect of camostat mesilate on heavy proteinuria in various nephropathies.
Matsubara M, Taguma Y, Kurosawa K, Hotta O, Suzuki K, Futaki G.
Clin Nephrol. 1989 Sep;32(3):119-23.

Effect of captopril on renal function during exercise in a patient with unilateral renal agenesis.
Hotta O, Taguma Y.
Nephron. 1988;48(4):331-2.

A femoral vein catheter with immobilized urokinase (UKFC) as an antithrombotic blood access.
Kitamoto Y, Fukui H, Iwabuchi K, Taguma Y, Monma H, Ishizaki M, Takahashi H, Nakayama M, Sekino H.
ASAIO Trans. 1987 Jul-Sep;33(3):136-9.

Useful antiglobulin crossmatch test for DST-sensitized patients.
Takahashi H, Okazaki H, Taguma Y, Oguma S, Jinbo M, Satake M, Iguchi A, Ohashi Y, Ishizaki M.
Transplant Proc. 1987 Feb;19(1 Pt 1):794-9.

Effect of captopril on heavy proteinuria in azotemic diabetics.
Taguma Y, Kitamoto Y, Futaki G, Ueda H, Monma H, Ishizaki M, Takahashi H, Sekino H, Sasaki Y.
N Engl J Med. 1985 Dec 26;313(26):1617-20.

Synthesis of the nonatetracontapeptide corresponding to the entire amino acid sequence of thymopoietin I and its effect on the low E-rosette-forming cells of a uremic patient.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1985 Apr;33(4):1583-91.

Deacetyl-thymosin beta 4: synthesis and effect on the impaired peripheral T-cell subsets in patients with chronic renal failure.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1984 Nov;32(11):4497-505.

Synthesis of six common amino acid sequence fragments of thymosins beta 4, beta 8 and beta 9 and determination of their effects on the low E-rosette forming cells of lupus nephritis patients.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1984 Jan;32(1):228-36.
Effects of synthetic thymosin beta 9 fragments on low E-rosette-forming cells of lupus nephritis patients.
Abiko T, Sekino H.
J Appl Biochem. 1983 Dec;5(6):446-52.

Synthesis of the nonatriacontapeptide corresponding to the entire amino acid sequence of calf thymosin beta 8 and its effect on the impaired T-cell subsets in patients with lupus nephritis.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1983 Apr;31(4):1320-9.

Effects of two synthetic serum thymic factor analogues and four thymic factor fragments on the low E-rosette forming cells in patients with chronic renal failure.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1982 Dec;30(12):4448-56.

Synthesis of the octadecapeptide corresponding to positions 32 to 49 of the revised amino acid sequence of thymopoietin II and its effect on low E-rosette forming cells of an aged patient with chronic renal failure.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1982 Sep;30(9):3271-7.

A study on endocrine disorder in patients with chronic renal failure. I. Synthesis and biological activity of human gastrin I.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1982 Jul;30(7):2604-10.

Deliberate buffy-coat transfusions and the risk of antibody formation.
Takahashi H, Iwaki Y, Terasaki PI, Okazaki H, Ishizaki M, Sekino H, Momma M, Takemoto S.
Transplant Proc. 1982 Jun;14(2):349-54.

Deacetyl-thymosin alpha 1: synthesis and immunological effect on lipoid nephrosis lymphocytes.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1982 May;30(5):1776-83.

Effects of synthetic thymopoietin fragments on low E-rosette forming cells in a patient with lupus nephritis.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1981 Nov;29(11):3320-5.

The effect of ubiquitin hexadecapeptide fragment on E-rosette forming cells of a uremic patient.
Abiko T, Sekino H.
Chem Pharm Bull (Tokyo). 1981 Oct;29(10):2949-55.

Effects of synthetic thymopoietin II fragments on E-rosette forming cells of a rheumatoid arthritis patient.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1981 Aug;29(8):2322-9.

Synthesis of six analogues and their two fragments related to L-alpha-hydroxyisovaleryl-Leu-Val-Phe-OMe as renin inhibitor.
Abiko T, Onodera I, Sekino H.
Biochem Biophys Res Commun. 1981 May 15;100(1):177-83.

Synthesis and immunological effects of thymosin alpha 1 and its fragments on inhibitory factor in minimal change nephrotic syndrome.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1980 Dec;28(12):3542-8.

The effect of thymosin alpha1 fragments on T-lymphocyte transformation in the uremic state.
Abiko T, Sekino H, Higuchi H.
Chem Pharm Bull (Tokyo). 1980 Nov;28(11):3411-5.

The effect of thymopoietin II fragments and their analogs on E-rosette forming cells in the uremic state.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1980 Aug;28(8):2507-11.
Characterization of an acidic tripeptide in neurotoxic dialysate.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1980 May;28(5):1629-33.

Effect of synthetic serum thymic factor fragments on the inhibition of sheep erythrocyte rosette formation by uremic toxin.
Abiko T, Onodera I, Sekino H, Higuchi H.
Chem Pharm Bull (Tokyo). 1980 Feb;28(2):667-9.

The effect of a synthetic thymosin alpha 1 fragment on the inhibition of E-rosette formation by the serum of a patient with nephrotic syndrome.
Abiko T, Onodera I, Sekino H.
Chem Pharm Bull (Tokyo). 1979 Dec;27(12):3171-5.

The effects of synthetic glucagon fragments on glucose-6-phosphate dehydrogenase. II.
Abiko T, Kumikawa M, Sekino H.
Chem Pharm Bull (Tokyo). 1979 Nov;27(11):2827-31.

Synthesis and effects of two peptide fragments of thymopoietin II on E-rosette forming cells in the uremic state.
Abiko T, Kumikawa M, Sekino H.
Chem Pharm Bull (Tokyo). 1979 Sep;27(9):2233-7.

The effect of STF and its analogs on T cells with cellular immunodeficiency.
Abiko T, Kumikawa M, Dazai S, Sekino H, Higuchi H.
Chem Pharm Bull (Tokyo). 1979 Sep;27(9):2207-11.

Isolation, structure and biological activity of the Trp-containing pentapeptide from uremic fluid.
Abiko T, Onodera I, Sekino H.
Biochem Biophys Res Commun. 1979 Aug 13;89(3):813-21.

Methylguanidine (MG) movement of serum and urine in chronic renal failure (author's transl).
Ishizaki M, Aoyama K, Uno C, Kobayashi S, Asano H, Takahashi H, Momma H, Sekino H, Shishito S, Saito H.
Nihon Jinzo Gakkai Shi. 1979 May;21(3):175-84.

Inhibition effect of rosette formation between human lymphocytes and sheep erythrocytes by specific heptapeptide isolated from uremic fluid and its analogs.
Abiko T, Kumikawa M, Sekino H.
Biochem Biophys Res Commun. 1979 Feb 28;86(4):945-52.

Study on influence of synthetic glucagon fragment on lymphocyte transformation. I.
Abiko T, Kumikawa M, Dazai S, Uno C, Ishizaki M, Takahashi H, Sekino H.
Chem Pharm Bull (Tokyo). 1978 Nov;26(11):3546-51.

Identification and synthesis of a heptapeptide in uremic fluid.
Abiko T, Kumikawa M, Higuchi H, Sekino H.
Biochem Biophys Res Commun. 1978 Sep 14;84(1):184-94.

Identification and synthesis of a tripeptide in ECUM fluid of an uremic patient.
Abiko T, Kumikawa M, Ishizaki M, Takahashi H, Sekino H.
Biochem Biophys Res Commun. 1978 Jul 28;83(2):357-64.

Studies on uremic toxins; structure-activity correlation in H-Asp(Gly)-OH.
Abiko T, Kumikawa M, Dazai S, Takahashi H, Ishizaki M, Sekino H.
Biochem Biophys Res Commun. 1978 May 30;82(2):707-15.

Ulnar nerve excitability in chronic renal failure (author's transl).
Ishizaki M, Takahashi H, Momma H, Aoyama K, Ohsawa C, Sekino H.
Nihon Jinzo Gakkai Shi. 1977 Sep;19(9):753-60.

Changes in peripheral blood T-cells and B-cells in chronic kidney failure.
Takahashi H, Momma H, Ishizaki M, Sekino H, Takahashi K.
Nihon Jinzo Gakkai Shi. 1975 Oct;17(10):867-78.

Papers published in the first 50 years since its establishment (1971- 2020)

[2] Collaborative research with other institutions

Intestinal necrosis related to administration of cation exchange resin without sorbitol: A retrospective analysis of 61 patients with end-stage renal diseases.
Murakami K, Nakamura Y, Miyasaka Y, Sato T, Kawagishi N, Sasano H.Pathol Int. 2020 May;70(5):270-279.

Steroid pulse therapy transiently destroys the discriminative histological structure of tonsils in IgA nephropathy: Tonsillectomy should be performed before or just after steroid pulse therapy.
Adachi M, Sato M, Miyazaki M, Hotta O, Hozawa K, Sato T, Taguma Y, Katori Y.
Auris Nasus Larynx. 2018 Dec;45(6):1206-1213.

Erratum to: Impact of hemoglobin levels on renal and non-renal clinical outcomes differs by chronic kidney disease stages: the Gonryo study.
Yamamoto T, Miyazaki M, Nakayama M, Yamada G, Matsushima M, Sato M, Sato T, Taguma Y, Sato H, Ito S.
Clin Exp Nephrol. 2017 Dec;21(6):1140.

Effects of cyclophosphamide on the prognosis of Japanese patients with renal vasculitis associated with anti-neutrophil cytoplasmic antibody-positive microscopic polyangiitis.
Iwabuchi M, Nakaya I, Tsuchiya Y, Shibagaki Y, Yamaguchi T, Fukuhara S, Oe Y, Sakuma T, Sato T, Taguma Y, Soma J.
Clin Exp Nephrol. 2016 Oct;20(5):712-719.

Impact of hemoglobin levels on renal and non-renal clinical outcomes differs by chronic kidney disease stages: the Gonryo study.
Yamamoto T, Miyazaki M, Nakayama M, Yamada G, Matsushima M, Sato M, Sato T, Taguma Y, Sato H, Ito S.
Clin Exp Nephrol. 2016 Aug;20(4):595-602.

Evidence-based clinical practice guidelines for IgA nephropathy 2014.
Yuzawa Y, Yamamoto R, Takahashi K, Katafuchi R, Tomita M, Fujigaki Y, Kitamura H, Goto M, Yasuda T, Sato M, Urushihara M, Kondo S, Kagami S, Yasuda Y, Komatsu H, Takahara M, Harabuchi Y, Kimura K, Matsuo S.　
Clin Exp Nephrol. 2016 Aug;20(4):511-535.

Prominent hyperplasia of renin-producing juxtaglomerular apparatus after chronic and complete blockade of the renin-angiotensin system in adult IgA nephropathy.
Abe M, Joh K, Ieiri N, Hotta O, Utsunomiya Y, Sato H, Kisu K, Sakumo N, Kiyomoto H, Sato T, Taguma Y, Ito S.
CEN Case Rep. 2015 Nov;4(2):228-232.

Relationship between low blood pressure and renal/cardiovascular outcomes in Japanese patients with chronic kidney disease under nephrologist care: the Gonryo study.
Yamamoto T, Nakayama M, Miyazaki M, Matsushima M, Sato T, Taguma Y, Sato H, Ito S.
Clin Exp Nephrol. 2015 Oct;19(5):878-86.

Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study).
Kitamoto Y, Arizono K, Fukui H, Tomita K, Kitamura H, Taguma Y, Imamura T.
PLoS One. 2015 Mar 5;10(3):e0118704.

Serum levels of galactose-deficient immunoglobulin (Ig) A1 and related immune complex are associated with disease activity of IgA nephropathy.
Suzuki Y, Matsuzaki K, Suzuki H, Okazaki K, Yanagawa H, Ieiri N, Sato M, Sato T, Taguma Y, Matsuoka J, Horikoshi S, Novak J, Hotta O, Tomino Y.
Clin Exp Nephrol. 2014 Oct;18(5):770-7.

Awareness about and educational intervention for chronic kidney disease in the general population: from a survey of participants at the CKD educational lecture in Miyagi prefecture.
Yanagisawa N, Miyazaki M, Sato H, Taguma Y, Ito S.
Nihon Jinzo Gakkai Shi. 2014;56(2):131-7.
Night-time blood pressure is associated with the development of chronic kidney disease in a general population: the Ohasama Study.
Kanno A, Kikuya M, Asayama K, Satoh M, Inoue R, Hosaka M, Metoki H, Obara T, Hoshi H, Totsune K, Sato T, Taguma Y, Sato H, Imai Y, Ohkubo T.
J Hypertens. 2013 Dec;31(12):2410-7.

Effect of allopurinol on cardiovascular incidence among hypertensive nephropathy patients: the Gonryo study.
Terawaki H, Nakayama M, Miyazawa E, Murata Y, Nakayama K, Matsushima M, Miyazaki M, Sato H, Sato M, Sato T, Taguma Y, Ito S.
Clin Exp Nephrol. 2013 Aug;17(4):549-53.

Survey of the effects of a column for adsorption of β2-microglobulin in patients with dialysis-related amyloidosis in Japan.
Gejyo F, Amano I, Ando T, Ishida M, Obayashi S, Ogawa H, Ono T, Kanno Y, Kitaoka T, Kukita K, Kurihara S, Sato M, Shin J, Suzuki M, Takahashi S, Taguma Y, Takemoto Y, Nakazawa R, Nakanishi T, Nakamura H, Hara S, Hiramatsu M, Furuya R, Masakane I, Tsuchida K, Motomiya Y, Morita H, Yamagata K, Yoshiya K, Yamakawa T; Society of β2-Microglobulin Adsorption Therapy.
Ther Apher Dial. 2013 Feb;17(1):40-7.

Increased risk of cardiovascular events and mortality among non-diabetic chronic kidney disease patients with hypertensive nephropathy: the Gonryo study.
Nakayama M, Sato T, Miyazaki M, Matsushima M, Sato H, Taguma Y, Ito S.
Hypertens Res. 2011 Oct;34(10):1106-10.

Different clinical outcomes for cardiovascular events and mortality in chronic kidney disease according to underlying renal disease: the Gonryo study.
Nakayama M, Sato T, Sato H, Yamaguchi Y, Obara K, Kurihara I, Sato K, Hotta O, Seino J, Miyata M, Takeuchi K, Nakayama K, Matsushima M, Otaka T, Kinoshita Y, Taguma Y, Ito S.
Clin Exp Nephrol. 2010 Aug;14(4):333-9.

A nationwide survey of rapidly progressive glomerulonephritis in Japan: etiology, prognosis and treatment diversity.
Koyama A, Yamagata K, Makino H, Arimura Y, Wada T, Nitta K, Nihei H, Muso E, Taguma Y, Shigematsu H, Sakai H, Tomino Y, Matsuo S; Japan RPGN Registry Group.
Clin Exp Nephrol. 2009 Dec;13(6):633-50.

A case of primary aldosteronism associated with renal artery stenosis and preclinical Cushing's syndrome.
Tsunoda K, Abe K, Yamada M, Kato T, Yaoita H, Taguma Y, Goto Y, Ioridani N.
Hypertens Res. 2008 Aug;31(8):1669-75.

Renal pathology of ANCA-related vasculitis: proposal for standardization of pathological diagnosis in Japan.
Joh K, Muso E, Shigematsu H, Nose M, Nagata M, Arimura Y, Yumura W, Wada T, Nitta K, Makino H, Taguma Y, Kaneoka H, Suzuki Y, Kobayashi M, Koyama A, Usui J, Hashimoto H, Ozaki S, Tomino Y, Yamagata K.
Clin Exp Nephrol. 2008 Aug;12(4):277-291.

High incidence of Dieulafoy's lesions in upper gastrointestinal bleeding associated with polyarteritis--clinical examination of patients of polyarteritis nodosa with rapidly progressive glomerulonephritis.
Ohara T, Kanoh Y, Taguma Y, Hashimoto H, Suzuki H, Sakai Y, Kondo F, Kameyama J, Tani N, Yoshino K, Kitajima M.
Hepatogastroenterology. 2008 May-Jun;55(84):821-5.

Anti-VEGF therapy for crescentic glomerulonephritis?
Kitamoto Y, Taguma Y, Arizono K, Imamura T.
Am J Kidney Dis. 2008 Apr;51(4):710-1.

Enhanced expression of C chemokine lymphotactin in IgA nephropathy.
Ou ZL, Hotta O, Natori Y, Sugai H, Taguma Y, Natori Y.
Nephron. 2002 Jun;91(2):262-9.

High prevalence and adverse effect of hepatitis C virus infection in type II diabetic-related nephropathy.
Soma J, Saito T, Taguma Y, Chiba S, Sato H, Sugimura K, Ogawa S, Ito S.
J Am Soc Nephrol. 2000 Apr;11(4):690-699.

Clinicopathological characteristics of interstitial foam cells in membranous nephropathy.
Kurihara I, Saito T, Soma J, Sato H, Hotta O, Taguma Y, Ito S.
Kidney Int Suppl. 1999 Jul;71:S144-6.

Increased plasma GDNF levels in patients with chronic renal diseases.
Onodera H, Nagata T, Kanazawa M, Taguma Y, Itoyama Y.
Nephrol Dial Transplant. 1999 Jun;14(6):1604-5.

Familial lobular glomerulopathy: first case report in Asia.
Sato H, Matsubara M, Marumo R, Soma J, Kurosawa K, Taguma Y, Saito T.
Am J Kidney Dis. 1998 Jun;31(6):E3.

Acoustic properties of dialysed kidney by scanning acoustic microscopy.
Sasaki H, Saijo Y, Tanaka M, Nitta S, Terasawa Y, Yambe T, Taguma Y.
Nephrol Dial Transplant. 1997 Oct;12(10):2151-4.

Clinicopathological study of interstitial foam cells in idiopathic membranous nephropathy. Consideration of the appearance of interstitial foam cells in renal tissue.
Kurihara I, Saito T, Hotta O, Taguma Y, Sudo K, Horigome I, Chiba S, Munakata T, Soma J, Ootaka T, Sato H, Abe K.
Nihon Jinzo Gakkai Shi. 1996 Feb;38(2):84-90.

Comparative study of cystic variations of the kidneys in haemodialysis and continuous ambulatory peritoneal dialysis patients.
Sasaki H, Terasawa Y, Taguma Y, Hotta O, Suzuki K, Nakamura K.
Int Urol Nephrol. 1996;28(2):247-54.

Minimal change nephrotic syndrome with predominant mesangial IgA deposits: clinicopathological study.
Soma J, Saito T, Sato H, Ootaka T, Suzuki M, Chiba S, Taguma Y, Yoshinaga K.
Nihon Jinzo Gakkai Shi. 1991 Feb;33(2):153-9.

Usefulness of ethanol-fixation and paraffin-embedding technique for renal biopsy specimens--application of immunoperoxidase technique.
Ootaka T, Saito T, Sato H, Suzuki M, Kinoshita Y, Seino J, Yoshinaga K, Yamakage K, Kurosawa K, Taguma Y, et al.
Nihon Jinzo Gakkai Shi. 1987 Jun;29(6):623-32.

Attenuation of pressor responses to norepinephrine and pitressin and potentiation of pressor response to angiotensin II by captopril in human subjects.
Imai Y, Abe K, Seino M, Haruyama T, Tajima J, Sato M, Goto T, Hiwatari M, Kasai Y, Yoshinaga K, Sekino H.
Hypertension. 1982 May-Jun;4(3):444-51.

Captopril attenuates pressor responses to norepinephrine and vasopressin through depletion of endogenous angiotensin II.
Imai Y, Abe K, Seino M, Haruyama T, Tajima J, Yoshinaga K, Sekino H.
Am J Cardiol. 1982 Apr 21;49(6):1537-9.

The inner ear dysfunction in hemodialysis patients.
Kusakari J, Kobayashi T, Rokugo M, Arakawa E, Ohyama K, Kawamoto K, Sekino H.
Tohoku J Exp Med. 1981 Dec;135(4):359-69.

Korean hemorrhagic fever among rural residents in Japan.
Umenai T, Watanabe M, Sekino H, Yokoyama S, Kaburagi T, Takahashi K, Lee HW, Ishida N.
J Infect Dis. 1981 Nov;144(5):460-3.

Hearing and vestibular function in the patients treated with hemodialysis.
Kusakari J, Kobayashi T, Rokugo M, Arakawa E, Kawamoto K, Sekino H.
Nihon Jibiinkoka Gakkai Kaiho. 1981 Apr;84(4):379-89.

Blood pressure regulation in chronic hypotensive and hypertensive patients with chronic renal failure.
Imai Y, Abe K, Otsuka Y, Sato M, Haruyama T, Ito T, Omata K, Yoshinaga K, Sekino H.
Jpn Circ J. 1981 Mar;45(3):303-14.

Plasma catecholamine concentration and plasma dopamine-beta-hydroxylase activity in patients undergoing chronic hemodialysis.
Sakuma H, Miura Y, Kobayashi K, Tomioka H, Adachi M, Furuyama T, Yoshinaga K, Sekino H, Ishizaki T.
Nihon Jinzo Gakkai Shi. 1980 Jun;22(6):753-62.

Plasma catecholamines and dopamine-beta-hydroxylase activity in chronic renal failure.
Kobayashi K, Miura Y, Tomioka H, Sakuma H, Adachi M, Furuyama T, Yoshinaga K, Ishizaki M, Sekino H.
Clin Chim Acta. 1979 Jul 16;95(2):317-23.

Renin-angiotensin-aldosterone system in chronic renal failure. Part 3) Change of the renin-angiotensin-aldosterone system after bilateral nephrectomy and kidney transplantation in chronic renal failure.
Fukuchi S, Nakajima K, Sekino H, Ishizaki M.
Nihon Jinzo Gakkai Shi. 1978 Apr;20(4):305-13.